Ibuprofen therapy resulted in significantly decreased tissue bacillary loads and increased survival in a new murine experimental model of active tuberculosis.

@article{Vilaplana2013IbuprofenTR,
  title={Ibuprofen therapy resulted in significantly decreased tissue bacillary loads and increased survival in a new murine experimental model of active tuberculosis.},
  author={Cristina Vilaplana and E Marzo and Gustavo Tapia and Jorge D{\'i}az and V Garc{\'i}a and Pere-Joan Cardona},
  journal={The Journal of infectious diseases},
  year={2013},
  volume={208 2},
  pages={
          199-202
        }
}
C3HeB/FeJ mice infected with Mycobacterium tuberculosis were used in an experimental animal model mimicking active tuberculosis in humans to evaluate the effect of antiinflammatory agents. No other treatment but ibuprofen was given, and it was administered when the animals' health started to deteriorate. Animals treated with ibuprofen had statistically significant decreases in the size and number of lung lesions, decreases in the bacillary load, and improvements in survival, compared with… Expand
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