Ibuprofen or acetaminophen for the acute treatment of migraine in children: a double-blind, randomized, placebo-controlled, crossover study.

@article{Hmlinen1997IbuprofenOA,
  title={Ibuprofen or acetaminophen for the acute treatment of migraine in children: a double-blind, randomized, placebo-controlled, crossover study.},
  author={Mirja L. H{\"a}m{\"a}l{\"a}inen and Kalle Hoppu and Esko Valkeila and Pirkko Santavuori},
  journal={Neurology},
  year={1997},
  volume={48 1},
  pages={
          103-7
        }
}
Efficacy of drugs for the acute treatment of migraine in children has not so far been studied in well controlled trials. We conducted a study to evaluate the efficacy of acetaminophen and ibuprofen. Eighty-eight children, aged 4.0 to 15.8 years, with migraine participated in a double-blind crossover study. Three attacks per child were treated in random order with single oral doses of 15 mg/kg acetaminophen, 10 mg/kg ibuprofen, and placebo at home. The primary end point, reduction in severe or… CONTINUE READING

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