Ibuprofen interferes with the efficacy of antihypertensive drugs. A randomized, double-blind, placebo-controlled trial of ibuprofen compared with acetaminophen.

@article{Radack1987IbuprofenIW,
  title={Ibuprofen interferes with the efficacy of antihypertensive drugs. A randomized, double-blind, placebo-controlled trial of ibuprofen compared with acetaminophen.},
  author={K L Radack and C C Deck and Sue Bloomfield},
  journal={Annals of internal medicine},
  year={1987},
  volume={107 5},
  pages={628-35}
}
STUDY OBJECTIVE To assess the effects of ibuprofen on blood pressure control in patients being treated with antihypertensive drugs. DESIGN Randomized, blinded, placebo-controlled, parallel trial of ibuprofen compared with acetaminophen and with placebo in 3-week treatment periods. SETTING A general internal medicine clinic at a university hospital. PATIENTS Forty-five patients with essential hypertension controlled by treatment with at least two antihypertensive drugs were enrolled. Of… CONTINUE READING