Ibuprofen-induced hepatotoxicity in patients with chronic hepatitis c: a case series

@article{Riley1998IbuprofeninducedHI,
  title={Ibuprofen-induced hepatotoxicity in patients with chronic hepatitis c: a case series},
  author={Thomas R. Riley and Jill Palmer Smith},
  journal={American Journal of Gastroenterology},
  year={1998},
  volume={93},
  pages={1563-1565}
}
Hepatitis C is a common chronic infection. Nonsteroidal anti-inflammatory drugs are commonly ingested both over-the-counter and by prescription. This case report describes three cases where ibuprofen use leads to a marked rise in hepatic transaminases with one case repeating on rechallenge. These cases support the recommendation of acetaminophen over nonsteroidal anti-inflammatory drug use in patients with chronic hepatitis C. 
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Acetaminophen hepatotoxicity with regular intake of alcohol: Analysis of instances of therapeutic misadventure. Hepatology 1995;22:767–73

  • HJ Zimmerman, WC Maddrey
  • AJG – September
  • 1998
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