Ibuprofen blocks time-dependent increases in hypoxic ventilation in rats.

@article{Popa2011IbuprofenBT,
  title={Ibuprofen blocks time-dependent increases in hypoxic ventilation in rats.},
  author={Dan Popa and Zhenxing Fu and Ariel Go and Frank L. Powell},
  journal={Respiratory physiology & neurobiology},
  year={2011},
  volume={178 3},
  pages={381-6}
}
Recently, inflammatory processes have been shown to increase O(2)-sensitivity of the carotid body during chronic sustained hypoxia [Liu, X., He, L., Stensaas, L., Dinger, B., Fidone, S., 2009. Adaptation to chronic hypoxia involves immune cell invasion and increased expression of inflammatory cytokines in rat carotid body. Am. J. Physiol. Lung Cell Mol. Physiol. 296, L158-L166]. We hypothesized that blocking inflammation with ibuprofen would reduce ventilatory acclimatization to hypoxia by… CONTINUE READING