Ibuprofen affects pro- and anti-inflammatory cytokine production by mononuclear cells of preterm newborns.

@article{Sirota2001IbuprofenAP,
  title={Ibuprofen affects pro- and anti-inflammatory cytokine production by mononuclear cells of preterm newborns.},
  author={Lea Sirota and D Shacham and Igor Punsky and Hanna Bessler},
  journal={Biology of the neonate},
  year={2001},
  volume={79 2},
  pages={103-8}
}
The in vitro effect of ibuprofen (IB) on the production of the proinflammatory cytokines interleukin (IL) 1beta, IL-6, and tumor necrosis factor alpha (TNF-alpha) and the anti-inflammatory cytokine IL-10 by cord blood mononuclear cells from preterm newborns was compared to that of peripheral blood mononuclear cells of adults. Mononuclear cells were incubated without or with lipopolysaccharide in the absence or presence of various concentrations of IB. The levels of IL-1beta, IL-6, TNF-alpha… CONTINUE READING