Ibufenac in the Treatment of Arthritis.


Ibufenac (4-isobutylphenyl-acetic acid, Fig. 1) has been shown to possess analgesic, anti-inflammatory, and antipyretic properties when administered to animals under experimental conditions (Adams, Cliffe, Lessel, and Nicholson, 1963). Toxicity studies indicated that this compound had a wide margin of safety, and preliminary clinical experience in patients… (More)


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