Iatrogenic lymphoproliferative disorders in non-transplantation settings.

  • Onsi W. Kamel
  • Published 1997 in
    Recent results in cancer research. Fortschritte…


Over the last decade, it has become clear that iatrogenic immunodeficiency-related lymphoproliferative disorders can occur in non-transplantation settings. These lymphoproliferative disorders occur predominantly in patients with rheumatologic diseases who are treated with immunomodulatory drugs. Like immunodeficiency-related lymphoproliferations in other settings, these represent a spectrum of lymphoid neoplasms and are frequently associated with Epstein-Barr virus. The distribution of histologic types of iatrogenic lymphoproliferations in non-transplantation settings appears to differ from that seen in other immunodeficiency settings with a probable increase in representation of Hodgkin's disease and lymphoproliferations resembling Hodgkin's disease. Recognition of these immunodeficiency-related lymphoproliferative disorders is important for appropriate patient management.


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@article{Kamel1997IatrogenicLD, title={Iatrogenic lymphoproliferative disorders in non-transplantation settings.}, author={Onsi W. Kamel}, journal={Seminars in diagnostic pathology}, year={1997}, volume={14 1}, pages={27-34} }