Iatrogenic hyperhomocysteinemia in patients with metabolic syndrome: a systematic review and metaanalysis.

@article{Ntaios2011IatrogenicHI,
  title={Iatrogenic hyperhomocysteinemia in patients with metabolic syndrome: a systematic review and metaanalysis.},
  author={G. Ntaios and C. Savopoulos and S. Chatzopoulos and D. Mikhailidis and Apostolos Hatzitolios},
  journal={Atherosclerosis},
  year={2011},
  volume={214 1},
  pages={
          11-9
        }
}
Metabolic syndrome (MetS) is associated with increased cardiovascular mortality and its management incorporates hypolipidemic, antidiabetic and antihypertensive drugs. However, several classes of these drugs, such as biguanides, fibrates and hydrochlorothiazide have been reported to raise circulating total homocysteine (tHcy) levels. During the last decades, numerous large-scale epidemiological studies have identified Hcy as a moderate independent cardiovascular risk factor. Therefore, drug… Expand
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  • M. Hristova
  • Biology, Medicine
  • The Eurasian journal of medicine
  • 2011
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