IXL, a new subunit of the mammalian Mediator complex, functions as a transcriptional suppressor.

@article{Wang2004IXLAN,
  title={IXL, a new subunit of the mammalian Mediator complex, functions as a transcriptional suppressor.},
  author={Yuequn Wang and Yongqing Li and Weiqi Zeng and Chuanbing Zhu and Jing Xiao and Wuzhou Yuan and Ying Wang and Zhenyu Cai and Junmei Zhou and Mingyao Liu and Xiushan Wu},
  journal={Biochemical and biophysical research communications},
  year={2004},
  volume={325 4},
  pages={1330-8}
}
Transcription factors play an essential role in altering gene expression. Much progress about transcription factors has been made toward the understanding of normal physiological processes, embryonic development, and human diseases. In the present study, we report the identification and characterization of a novel human gene, (Drosophila) intersex-like (IXL), from a human embryonic heart cDNA library. IXL encodes a putative protein of 221 amino acids. The protein is conserved across different… CONTINUE READING