ISWI chromatin remodeling complexes in the DNA damage response

  title={ISWI chromatin remodeling complexes in the DNA damage response},
  author={{\"O}zge Z Aydin and Wim Vermeulen and Hannes Lans},
  booktitle={Cell cycle},
Regulation of chromatin structure is an essential component of the DNA damage response (DDR), which effectively preserves the integrity of DNA by a network of multiple DNA repair and associated signaling pathways. Within the DDR, chromatin is modified and remodeled to facilitate efficient DNA access, to control the activity of repair proteins and to mediate signaling. The mammalian ISWI family has recently emerged as one of the major ATP-dependent chromatin remodeling complex families that… CONTINUE READING
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