• Corpus ID: 53463523

ISOLATION OF TSH-RESPONSIVE HUMAN THYROCYTES\x=req-\ ANALYSIS OF VARIOUS THYROID TUMOURS

@inproceedings{Nolde2008ISOLATIONOT,
  title={ISOLATION OF TSH-RESPONSIVE HUMAN THYROCYTES\x=req-\ ANALYSIS OF VARIOUS THYROID TUMOURS},
  author={Siegmar Nolde and Matthias Schumacher and Helmuth Hilz},
  year={2008}
}
A method for the isolation of hormone-responsive thyrocyte suspensions from human tumours is described. Cells from normal and adenomatous thyroid tissue responded to thyroid stimulating hormone (TSH) by a concentration-dependent increase in cAMP. Bovine TSH usually produced half-maximal elevation of cAMP levels at concentrations between 2 and 4 mU/ml. Human TSH caused half\x=req-\ maximal stimulation at 3\p=n-\8 times lower concentrations indicating considerable species specificity of the human… 

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