ISG15: the immunological kin of ubiquitin.

@article{Ritchie2004ISG15TI,
  title={ISG15: the immunological kin of ubiquitin.},
  author={Kenneth J Ritchie and Dong-er Zhang},
  journal={Seminars in cell & developmental biology},
  year={2004},
  volume={15 2},
  pages={237-46}
}
Since the discovery of ubiquitin in 1975, the poly-ubiquitylation pathway has earned a prominent place in biomedical research as the "garbage disposal" system of the cell. Modification with poly-ubiquitin chains plays an important role in normal protein turnover and also in removing damaged or misfolded proteins. More recently, the elucidation of mono-ubiquitylation of protein substrates has shown additional important roles for ubiquitylation in processes, such as transcriptional regulation… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
60 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 60 extracted citations

Similar Papers

Loading similar papers…