ISEcp1-mediated transposition and homologous recombination can explain the context of bla(CTX-M-62) linked to qnrB2.

@article{Zong2010ISEcp1mediatedTA,
  title={ISEcp1-mediated transposition and homologous recombination can explain the context of bla(CTX-M-62) linked to qnrB2.},
  author={Zhiyong Zong and Sally R. Partridge and Jonathan R. Iredell},
  journal={Antimicrobial agents and chemotherapy},
  year={2010},
  volume={54 7},
  pages={3039-42}
}
bla(CTX-M-62), a C508T variant of bla(CTX-M-3b), was transferred from Klebsiella pneumoniae JIE137 on a conjugative plasmid together with a class 1 integron containing the dfrA12-gcuF-aadA2 cassette array, ISCR1, and qnrB2. bla(CTX-M-62) lies between intact and rearranged copies of ISEcp1 in a configuration that can be explained by a combination of transposition and homologous recombination and which also illustrates the ability of ISEcp1 to mobilize an adjacent gene as part of transposition… CONTINUE READING

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