IS6110-mediated deletions of wild-type chromosomes of Mycobacterium tuberculosis.

  title={IS6110-mediated deletions of wild-type chromosomes of Mycobacterium tuberculosis.},
  author={Zack Fang and Christine Doig and Dervla T. D. Kenna and Nat Smittipat and Prasit Palittapongarnpim and Brian Watt and Ken James Forbes},
  journal={Journal of bacteriology},
  volume={181 3},
The ipl locus is a site for the preferential insertion of IS6110 and has been identified as an insertion sequence, IS1547, in its own right. Various deletions around the ipl locus of clinical isolates of Mycobacterium tuberculosis were identified, and these deletions ranged in length from several hundred base pairs up to several kilobase pairs. The most obvious feature shared by these deletions was the presence of an IS6110 copy at the deletion sites, which suggested two possible mechanisms for… CONTINUE READING

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