IRIS: intermolecular RNA interaction search.

  title={IRIS: intermolecular RNA interaction search.},
  author={D. D. Pervouchine},
  journal={Genome informatics. International Conference on Genome Informatics},
  volume={15 2},
  • D. D. Pervouchine
  • Published 2004
  • Medicine, Biology
  • Genome informatics. International Conference on Genome Informatics
  • Here we present IRIS, a method for prediction of RNA-RNA interactions that is based on dynamic programming and extends current RNA secondary structure prediction approaches. Using this method we have found a number of interesting refinements to the structures of RNA-RNA complexes that have been studied previously and predicted novel targets for several known regulatory RNAs in E. coli. The computational time and memory usage of IRIS are O(n(3)m(3)) and O(n(2)m(2)), respectively, where n and m… CONTINUE READING
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