IQGAPs as Key Regulators of Actin-cytoskeleton Dynamics.

  title={IQGAPs as Key Regulators of Actin-cytoskeleton Dynamics.},
  author={Takashi Watanabe and Shujie Wang and Kozo Kaibuchi},
  journal={Cell structure and function},
  volume={40 2},
The actin-cytoskeleton plays a critical role in various biological processes, including cell migration, development, tissue remodeling, and memory formation. Both extracellular and intracellular signals regulate reorganization of the actin-cytoskeleton to modulate tissue architecture and cellular morphology in a spatiotemporal manner. Since the discovery that activation of Rho family GTPases induces actin-cytoskeleton reorganization, the mode of action of Rho family GTPases has been extensively… CONTINUE READING

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