IQGAP1 interacts with Aurora-A and enhances its stability and its role in cancer.

Abstract

IQGAP1, a ubiquitously expressed scaffold protein, has been identified in a wide range of organisms. It participates in multiple aspects of cellular events by binding to and regulating numerous interacting proteins. In our present study, we identified a new IQGAP1 binding protein named Aurora-A which is an oncogenic protein and overexpressed in various… (More)
DOI: 10.1016/j.bbrc.2012.03.112

Topics

  • Presentations referencing similar topics