IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity.

Abstract

During development, the Hippo signaling pathway regulates key physiological processes, such as control of organ size, regeneration, and stem cell biology. Yes-associated protein (YAP) is a major transcriptional co-activator of the Hippo pathway. The scaffold protein IQGAP1 interacts with more than 100 binding partners to integrate diverse signaling pathways… (More)
DOI: 10.1074/jbc.M116.732529

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