IPET study: an FLT-PET window study to assess the activity of the steroid sulfatase inhibitor irosustat in early breast cancer

@inproceedings{Palmieri2017IPETSA,
  title={IPET study: an FLT-PET window study to assess the activity of the steroid sulfatase inhibitor irosustat in early breast cancer},
  author={Carlo Palmieri and Richard M. Szydlo and Marie Miller and Laura Barker and Neva H. Patel and Hironobu Sasano and Tara D. Barwick and Henry Ho Ching Tam and Dimitri John Hadjiminas and Jasmin Lee and Abeer Adel Mohammed Shaaban and Hanna Nicholas and R C Coombes and Laura M. Kenny},
  booktitle={Breast Cancer Research and Treatment},
  year={2017}
}
Steroid sulfatase (STS) is involved in oestrogen biosynthesis and irosustat is a first generation, irreversible steroid sulfatase inhibitor. A pre-surgical window-of-opportunity study with irosustat was undertaken in estrogen receptor-positive (ER+) breast cancer to assess the effect of irosustat on tumour cell proliferation as measured by 3′-deoxy-3′-[18F… CONTINUE READING