IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors.

@article{Liu2005IPCPT,
  title={IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors.},
  author={Yong-Jun Liu},
  journal={Annual review of immunology},
  year={2005},
  volume={23},
  pages={
          275-306
        }
}
Type 1 interferon-(alpha, beta, omega)-producing cells (IPCs), also known as plasmacytoid dendritic cell precursors (pDCs), represent 0.2%-0.8% of peripheral blood mononuclear cells in both humans and mice. IPCs display plasma cell morphology, selectively express Toll-like receptor (TLR)-7 and TLR9, and are specialized in rapidly secreting massive amounts of type 1 interferon following viral stimulation. IPCs can promote the function of natural killer cells, B cells, T cells, and myeloid DCs… CONTINUE READING
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