IODINE DEFICIENCY DISORDERS (IDD) AND THEIR ERADICATION

@article{Hetzel1983IODINEDD,
  title={IODINE DEFICIENCY DISORDERS (IDD) AND THEIR ERADICATION},
  author={B. Hetzel},
  journal={The Lancet},
  year={1983},
  volume={322},
  pages={1126-1129}
}
Disorders resulting from severe iodine deficiency affect more than 400 million people in Asia alone. These disorders include stillbirths, abortions, and congenital anomalies; endemic cretinism, characterised most commonly by mental deficiency, deaf mutism, and spastic diplegia and lesser degrees of neurological defect related to fetal iodine deficiency; and impaired mental function in children and adults with goitre associated with subnormal concentrations of circulating thyroxine. Use of the… Expand
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TLDR
It is concluded that intramuscular iodised oil is effective in the prevention of endemic cretinism and that, for it to be effective, it should be given prior to conception, suggesting that severe iodine deficiency in the mother produces neurological damage during fetal development. Expand
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Urgent implementation of iodine prophylaxis is imperative and the benefits of modern technological advancement for early detection and prompt treatment of thyroid related developmental abnormalities of the brain among the new borns in these areas, should be utilised as an interim measure to prevent further such damages. Expand
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TLDR
Children born to mothers given iodine were significantly faster and more accurate in tests of manual function than children from control mothers, indicating that iodine deficiency may lead to a spectrum of subclinical deficits which place the children at a developmental disadvantage. Expand
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