Corpus ID: 54072275

INVOSSA TM – a cell and gene therapy for osteoarthritis

  title={INVOSSA TM – a cell and gene therapy for osteoarthritis},
  author={K. Emanuel and K. Mader and M. Peeters and I. Kingma and C.M.E. Rustenburg and Pieter-Paul A. Vergroesen and Sammon and T. Smit},
INTRODUCTION: Osteoarthritis (OA) is a debilitating and painful disease that is growing in incidence due to the aging population. Current treatment modalities attempt to address pain and improve function, but no treatment is curative. Until recently, OA was seen as the result of joint trauma, but is now recognized as a chronic, inflammatory process. OA’s inflammatory process is an imbalance between pro-inflammatory and anti-inflammatory cytokines. This process can be interrupted by TGF-β1… Expand

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ACKNOWLEDGEMENTS: This work was supported by the DFG Research network (FOR2407/1): ExCarBon SP7
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