• Corpus ID: 212453368


  author={Alankrita Dashora and Kanika Sharma},
Peptic ulcer is an excoriated area of the gastric or duodenal mucosa caused by action of the gastric juice. It is a chronic, recurrent and the most predominant disease of the gastrointestinal (GI) diseases, which is generally caused by a lack of equilibrium between the gastric aggressive factors and the mucosal defensive factors. Many indigenous Indian medicinal plants have been found to successfully manage GI diseases. In the present study Caralluma attenuata (C. attenuata) locally known as… 

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INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES (Int. J. of Pharm. Life Sci.) Ethnopharmacological evaluation of antiulcer activity of Caralluma attenuta

Caralluma attenuata has the potential to be used as an antiulcer in rats and maintains the integrity of gastric mucosa by virtue of its effect on offensive and defensive Gastric mucosal factors.

The effect of a traditional preparation of copper, tamrabhasma, on experimental ulcers and gastric secretion.

Experimental evaluation of Bocopa monniera on rat gastric ulceration and secretion.

Ulcer protective effect of BMJ may be due to its effect on mucosal defensive factors like enhanced mucin secretion, mucosal glycoprotein and decreased cell shedding rather than on offensive factors such as acid and pepsin.

Effect of some Sitavirya drugs on gastric secretion and ulceration.

Four Sitavirya plants were found to protect the animals against 2 hr cold restraint stress and pylorus ligation-induced gastric and cysteamine-induced duodenal ulcers, however, they were ineffective against acute aspirin- induced gastric ulcers.

Study of the antisecretory and antiulcer mechanisms of a new indenopirydazinone derivative in rats.

The present study investigates the antisecretory and antiulcer mechanisms of a new indenopyridazinone derivative previously reported to inhibit gastric acid secretion in pylorus-ligated rats and to

Antioxidant properties of natural compounds used in popular medicine for gastric ulcers.

  • M. RepettoS. Llesuy
  • Biology
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
  • 2002
The role of natural antioxidants derived from popular plants to reduce or prevent the oxidative stress in gastric ulcer induced by ethanol is considered.

Effect of mild irritant on gastric mucosal offensive and defensive factors.

DW did not afford any protection while HS showed significant ulcer protective effects in all gastric ulcer models studied, and the cytoprotective effect of HS seemed to be not only due to its effect on gastric acid secretion but also its effecton mucosal defensive factors like enhanced mucin secretion and decreased cell shedding.

Sakun Publishing House (SPH): IJPLS I NTERNATIONAL J OURNAL OF P HARMACY & L IFE S CIENCES (Int. J. of Pharm. Life Sci.) Ulcer Healing Properties of Ethanolic Extract of P.oleracea in Streptozotocin-induced Diabetic Rats

Of all the three doses of P. oleracea tested, the dose of 250 mg/kg exhibited dose-dependent significant ulcer healing property along with the better antidiabetic property as compared to other two doses, which can be beneficial in the treatment of gastric ulcers and diabetes.