Corpus ID: 1048255

INFLUENCE OF ORGANIC SOLVENTS ON NANOPARTICLE FORMATION AND SURFACTANTS ON RELEASE BEHAVIOUR IN-VITRO USING COSTUNOLIDE AS MODEL ANTICANCER AGENT

@inproceedings{Vineeth2014INFLUENCEOO,
  title={INFLUENCE OF ORGANIC SOLVENTS ON NANOPARTICLE FORMATION AND SURFACTANTS ON RELEASE BEHAVIOUR IN-VITRO USING COSTUNOLIDE AS MODEL ANTICANCER AGENT},
  author={P. Vineeth and P. Vadaparthi and K. Kumar and B. Babu and A. Rao and K. S. Babu},
  year={2014}
}
Objective: The objective of this study was to screen different solvents for optimizing nanoparticle preparation in terms of particle size,entrapment efficiency, and surfactants on release behaviour in-vitro. Methods: Nanoparticles(NP’s) of poly (d,l-lactic-co-glycolic acid) (PLGA),containing costunolide were prepared following modified oil-in-water single emulsion solvent evaporation technique using polyvinyl alcohol (PVA) and tween80 as stabilizers. NPs were characterized in terms of surface… Expand
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