INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow

@article{Adams2000INCENPBT,
  title={INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow},
  author={Richard R. Adams and S. P. Wheatleya and A. M. Gouldsworthy and Stefanie Kandels-Lewis and Mar Carmena and Carl G W Smythe and Dietlind L. Gerloff and William C Earnshaw},
  journal={Current Biology},
  year={2000},
  volume={10},
  pages={1075-1078}
}
Cytoskeletal rearrangements during mitosis must be co-ordinated with chromosome movements. The 'chromosomal passenger' proteins [1], which include the inner centromere protein (INCENP [2]), the Aurora-related serine-threonine protein kinase AIRK2 [3,4] and the unidentified human autoantigen TD-60 [5], have been suggested to integrate mitotic events. These proteins are chromosomal until metaphase but subsequently transfer to the midzone microtubule array and the equatorial cortex during anaphase… CONTINUE READING
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