IN VIVO INTERACTION OF PROPYLTHIOURACIL WITH SODIUM IODIDE (Na131I) RADIOPHARMACEUTICAL IN RATS (Rattus norvegicus)

@inproceedings{Daruwati2017INVI,
  title={IN VIVO INTERACTION OF PROPYLTHIOURACIL WITH SODIUM IODIDE (Na131I) RADIOPHARMACEUTICAL IN RATS (Rattus norvegicus)},
  author={Isti Daruwati and Iim Halimah and Isa Mahendra and F DwiDeasy and A. Hanafiah Ws},
  year={2017}
}
IN VIVO INTERACTION OF PROPYLTHIOURACIL WITH SODIUM IODIDE (Na131I) RADIOPHARMACEUTICAL IN RATS (Rattus norvegicus).. The aim of this research is to determine the effect of propylthiouracil (PTU) treatment to pharmacokinetics interaction and biodistribution profile of Na131I radiopharmaceuticals. Three groups of animal model were used in this experiment, i.e. experimental animals which given PTU for 1 time (onset or A groups), PTU for six days (B Groups) and without treatment (control or C… 

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In Vivo Interaction of Propylthiouracil Wit Sodium Iodide (NaI)

  • 2020

IN VIVO INTERACTION OF PROPYLTHIOURACIL WITH SODIUM IODIDE (Na131I) RADIOPHARMACEUTICAL IN RATS (Rattus norvegicus)

TLDR
It was concluded that PTU treatment cannot alter absorption, distribution and elimination half time Na131I, but the accumulation in thyroid was decrease in A group to control.

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