Corpus ID: 3904229

IN-VIVO IMMUNOMODULATORY POTENTIAL OF STANDARDIZED PUERARIA TUBEROSA EXTRACT AND ITS ISOFLAVONOIDS

@inproceedings{Maji2014INVIVOIP,
  title={IN-VIVO IMMUNOMODULATORY POTENTIAL OF STANDARDIZED PUERARIA TUBEROSA EXTRACT AND ITS ISOFLAVONOIDS},
  author={Amal K. Maji and Subhadip Mahapatra and Debdulal Banerjee},
  year={2014}
}
Objective: The present study was designed to investigate the immunomodulatory potential of Pueraria tuberosa tuber extract and isoflavones puerarin, daidzein and genistein in rats. Methods: The immunomodulatory potential of standardized P. tuberosa tuber extract (100-200 mg/kg; p.o.) and isoflavones puerarin (25-50 mg/kg; p.o.), daidzein (25-50 mg/kg; p.o.) and genistein (25-50 mg/kg; p.o.) was evaluated in swiss albino rats. Immunomodulatory potential was evaluated against sheep red blood… Expand

Figures and Tables from this paper

IMMUNOMODULATORY ACTIVITY OF MUNTINGIA CALABURA L. FRUITS USING CARBON CLEARANCE ASSAY AND THEIR TOTAL FLAVONOID AND PHENOLIC CONTENTS
Objective: Muntingia calabura L fruits have several advantages for health and can be consumed as alternative medicine. This study aims to evaluate the immunomodulatory activity of methanol extractExpand
Pueraria tuberosa: a review on its phytochemical and therapeutic potential
TLDR
Traditional applications, current knowledge on the phytochemistry, pharmacology and toxicology of P. tuberosa, and plausible hypotheses about how various isoflavones particularly puerarin, genistein and daidzein, individually or collectively, may be responsible for the therapeutic potential against a wide range of ailments are provided. Expand
Pueraria tuberosa: A Review on Traditional Uses, Pharmacology, and Phytochemistry
TLDR
The objective of the present review is to compile and update the published data on traditional uses, pharmacological potential, and phytochemistry of compounds isolated from the plant Pueraria tuberosa, which possesses an extensive range of pharmacological activities. Expand
Evaluation of the Immunomodulatory Activity of the Roots of Ichnocarpus frutescens
The objective of the present study was to investigate the immunomodulatory activity of the roots of Ichnocarpus frutescents R.Br. In the present study Pet. Ether, Chloroform and Methanolic fractionsExpand
A comprehensive review on Pueraria: Insights on its chemistry and medicinal value.
TLDR
In this review, the scientific information on Pueraria reported until May 2020 were analysed and summarized logically to appreciate its health benefits and to identify research gaps. Expand
Immunomodulatory Effect of Methanolic Extract and Ethyl Acetate Fraction of Bengkoang (Pachyrhizus erosus (L.) Urban) Tuber in Mice
Currently, public interest in the use of herbal medicine as an agent that can modulate the immune system is increasing. Immunomodulators are compounds that can modulate the immune system byExpand
Evaluation of Anti-Inflammatory Properties of Isoorientin Isolated from Tubers of Pueraria tuberosa
TLDR
The results suggest that isoorientin, a selective inhibitor of COX-2, not only exerts anti-inflammatory effects in LPS induced RAW cells and carrageenan induced inflammatory model systems but also exhibits potent antioxidant properties. Expand
Isoorientin, a Selective Inhibitor of Cyclooxygenase-2 (COX-2) from the Tubers of Pueraria tuberosa
TLDR
The structures of the isolates were determined by mass spectrometry and 2D-NMR techniques including HSQC, HMBC, NOESY and 1H-1H COSY experiments and are the first report of their isolation from a Pueraria species. Expand
Development and Evaluation of Herbal Tablet Loaded with Pueraria tuberosa Water Extract with Use of Different Excipients
Aim: The aim of present paper is to develop the best quality of low cost tablets and with better effectiveness . Material and Methods: In this experiment we have used starch and some other excipientsExpand
Histopathological Study Of Different Organs Of Charles Foster Rats Under The Exposure Of Pueraria tuberosa
TLDR
No adverse alterations in cardiac fibers of the heart, size and shapes in crypts and villi of intestine, seminiferous tubules and spermatozoa count in testis, three zones of adrenal gland, and spleen were seen in all treated groups of PTWE. Expand
...
1
2
...

References

SHOWING 1-10 OF 26 REFERENCES
In-vivo immunomodulatory activity of standardized Stereospermum suaveolens (Roxb.) DC. root extract
TLDR
The findings suggest that SSRE can able to stimulate the innate defence mechanisms of an individual and it can be considered as an alternative therapy to boost the innate immune functions during the impaired immunological conditions. Expand
In vitro and in vivo immunomodulatory activities of iridoids fraction from Barleria prionitis Linn.
TLDR
The present investigation reveals that IFBp is a potent immunostimulant, stimulating both the specific and non-specific immune mechanisms. Expand
Isoflavonoids production in callus culture of Pueraria tuberosa, the Indian kudzu.
TLDR
The production of four isoflavonoids (puerarin, genistin, genistein and daidzein) in the callus cultures of P. tuberosa was studied by manipulating the plant growth regulators and sucrose concentration in the medium and organogenesis was not recorded in callus on any of these treatments. Expand
Immunomodulatory activities of the ethanolic extract of Caesalpinia bonducella seeds.
TLDR
The results obtained in this study indicate that Caesalpinia bonducella possesses potential immunomodulatory activity and has therapeutic potential for the prevention of autoimmune diseases. Expand
Nootropic activity of tuber extract of Pueraria tuberosa (Roxb).
TLDR
The results indicate that nootropic activity observed with ALE and AQE of tuber extracts of P. tuberosa could be through improved learning and memory either by augmenting the noradrenaline (NA) transmission or by interfering with 5-hydroxytryptamine (5-HT) release. Expand
Immunomodulatory and antioxidative potential of herb (Pueraria tuberosa) in mice using milk as the carrier
TLDR
Group P and Group PM showed significantly higher reduced glutathione level and significantly lowered thiobarbituric acid reactive substances levels in liver and red blood cells as compared to control. Expand
Immunomodulatory activity of aqueous extract of Achillea wilhelmsii C. Koch in mice.
TLDR
Overall, A. wilhelmsii showed a stimulatory effect on both humoral and cellular immune functions in mice, and showed a significant increase in the DTH response at the dose of 100 mg/kg. Expand
Immunomodulatory effects of aqueous extract of Tridax procumbens in experimental animals.
TLDR
The results suggest that TPEIF influences both humoral as well as cell mediated immune system vis-a-vis assists in genesis of improved antibody response against specific clinical antigen. Expand
A validated RP-HPLC-UV method for quantitative determination of puerarin in Pueraria tuberosa DC tuber extract
TLDR
The developed RP-HPLC method is very simple and rapid with excellent specificity, accuracy and precision which can be useful for the routine analysis and quantitative estimation of puerarin in plant extracts and formulations. Expand
Immunomodulatory effects of two sapogenins 1 and 2 isolated from Luffa cylindrica in Balb/C mice.
TLDR
Sapogenins 1 and 2 showed dose relative immunostimulatory effect on in vivo immune functions in mice and showed significant dose-dependent decrease and increase in lymphocyte proliferation assay and phagocytic activity of macrophages. Expand
...
1
2
3
...