IMUP-1 and IMUP-2 genes are up-regulated in human ovarian epithelial tumors.

Abstract

BACKGROUND Normal cells lose their ability to divide after a finite number of cell divisions. Under the influence of Simian virus 40 (SV 40) large T-antigen, which interacts with the cell cycle regulators p53 and pRb, cells enter a phase of an extended pre-immortalized cells. Immortalization-up-regulated protein 1 (IMUP-1) and immortalization-up-regulated… (More)

Topics

  • Presentations referencing similar topics