IMRT for adjuvant radiation in gastric cancer: a preferred plan?

@article{Ringash2005IMRTFA,
  title={IMRT for adjuvant radiation in gastric cancer: a preferred plan?},
  author={Jolie Ringash and G. Perkins and James D Brierley and Gina A. Lockwood and Mohammad Rafiqul Islam and Pamela A. Catton and Bernard J. Cummings and John J. Kim and Rebecca Wong and Laura Dawson},
  journal={International journal of radiation oncology, biology, physics},
  year={2005},
  volume={63 3},
  pages={
          732-8
        }
}
  • J. Ringash, G. Perkins, L. Dawson
  • Published 1 October 2003
  • Medicine, Physics
  • International journal of radiation oncology, biology, physics
Can we obtain planning goals for conformal techniques in neoadjuvant and adjuvant radiochemotherapy for gastric cancer patients?
  • W. Leszczyński, P. Polanowski, J. Wydmański
  • Medicine, Physics
    Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
  • 2016
Evaluation of dose coverage to target volume and normal tissue sparing in the adjuvant radiotherapy of gastric cancers: 3D-CRT compared with dynamic IMRT
TLDR
This study showed that a better target coverage and significant dose reduction to OARs could be achieved with the IMRT plans, and can be preferred with caution for organ motion.
Kidney-Sparing Radiotherapy by Multiple-Field Three-Dimensional Technique in the Postoperative Management of Patients with Gastric Cancer: Comparison with Standard Two-Field Conformal Technique
TLDR
The right kidney may be largely spared from irradiation; with respect to the two-field technique, the left kidney may receive a significantly reduced dose; however, the liver receives an increased dose that warrants careful long-term monitoring of hepatic function.
Intensity-modulated radiation therapy in the treatment of gastric cancer: early clinical outcome and dosimetric comparison with conventional techniques.
TLDR
In an initial cohort of seven patients, 50.4 Gy delivered by IMRT is well tolerated and safe, and target coverage with IMRT was excellent, with 98+/-1% of the target receiving >or=100% ofthe dose.
Clinical Outcomes for Gastric Cancer following Adjuvant Chemoradiation Utilizing Intensity Modulated versus Three-Dimensional Conformal Radiotherapy
TLDR
This study demonstrates that adjuvant chemoradiation for gastric cancer with IMRT to 50.4 Gy was well-tolerated and compared similarly in toxicity with 3DCRT to 45 Gy.
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References

SHOWING 1-10 OF 13 REFERENCES
Optimization of Dose Distributions for Adjuvant Locoregional Radiotherapy of Gastric Cancer by IMRT
TLDR
IMRT has the potential to deliver efficient doses to target volumes in the upper abdomen, while delivering dose to organs at risk in a more advantageous fashion than a conventional technique.
Neoadjuvant or adjuvant therapy for resectable gastric cancer? A practice guideline.
TLDR
Patients with resectable gastric cancer whose tumours have penetrated the muscularis propria or involve regional lymph nodes should be considered for adjuvant combined chemoradiotherapy, and Physicians and patients should understand the tradeoffs between survival benefit and toxicity and cost before making treatment decisions.
A comparison of combination chemotherapy and combined modality therapy for locally advanced gastric carcinoma
TLDR
It is possible that the superior late survival achieved with combined modality therapy in this program can be further improved with measures to decrease the toxicity of upper abdominal irradiation, and with the use of more effective forms of chemotherapy.
Chemoradiotherapy after Surgery Compared with Surgery Alone for Adenocarcinoma of the Stomach or Gastroesophageal Junction
TLDR
This investigation investigated the effect of surgery plus postoperative (adjuvant) chemoradiotherapy on the survival of patients with resectable adenocarcinoma of the stomach or gastroesophageal junction.
Gastric adenocarcinoma--management of the primary disease.
TLDR
Suggestions for effective adjuvant therapies, based on the realization that most gastric cancer has become a systemic disease by the time of diagnosis, are apparent from the clinical trials to date.
Effects of motion on the total dose distribution.
TLDR
An overview of different studies that looked at the effect of organ motion and setup errors on radiation therapy dose distributions, both from a qualitative and quantitative point of view are given.
...
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