IMRT for adjuvant radiation in gastric cancer: a preferred plan?

@article{Ringash2005IMRTFA,
  title={IMRT for adjuvant radiation in gastric cancer: a preferred plan?},
  author={Jolie Ringash and G. Perkins and James D Brierley and Gina A. Lockwood and Mohammad Rafiqul Islam and Pamela A. Catton and Bernard J. Cummings and John J. Kim and Rebecca Wong and Laura Dawson},
  journal={International journal of radiation oncology, biology, physics},
  year={2005},
  volume={63 3},
  pages={
          732-8
        }
}
  • J. Ringash, G. Perkins, L. Dawson
  • Published 1 October 2003
  • Medicine, Physics
  • International journal of radiation oncology, biology, physics
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96 Citations
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96 Citations

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Evaluation of dose coverage to target volume and normal tissue sparing in the adjuvant radiotherapy of gastric cancers: 3D-CRT compared with dynamic IMRT
TLDR
This study showed that a better target coverage and significant dose reduction to OARs could be achieved with the IMRT plans, and can be preferred with caution for organ motion.
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Kidney-Sparing Radiotherapy by Multiple-Field Three-Dimensional Technique in the Postoperative Management of Patients with Gastric Cancer: Comparison with Standard Two-Field Conformal Technique
TLDR
The right kidney may be largely spared from irradiation; with respect to the two-field technique, the left kidney may receive a significantly reduced dose; however, the liver receives an increased dose that warrants careful long-term monitoring of hepatic function.
Can all centers plan intensity-modulated radiotherapy (IMRT) effectively? An external audit of dosimetric comparisons between three-dimensional conformal radiotherapy and IMRT for adjuvant chemoradiation for gastric cancer.
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In an initial cohort of seven patients, 50.4 Gy delivered by IMRT is well tolerated and safe, and target coverage with IMRT was excellent, with 98+/-1% of the target receiving >or=100% ofthe dose.
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TLDR
This study demonstrates that adjuvant chemoradiation for gastric cancer with IMRT to 50.4 Gy was well-tolerated and compared similarly in toxicity with 3DCRT to 45 Gy.
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