IMPORTANCE OF DOSE OF NEUTRALISING ANTIBODIES IN TREATMENT OF ARGENTINE HAEMORRHAGIC FEVER WITH IMMUNE PLASMA

@article{Enria1984IMPORTANCEOD,
  title={IMPORTANCE OF DOSE OF NEUTRALISING ANTIBODIES IN TREATMENT OF ARGENTINE HAEMORRHAGIC FEVER WITH IMMUNE PLASMA},
  author={DeliaA. Enria and NestorJ. Fernandez and AnaM. Briggiler and SilvanaC. Levis and JulioI. Maiztegui},
  journal={The Lancet},
  year={1984},
  volume={324},
  pages={255-256}
}
P6 a retrospective study outcome in patients with Argentine haemorrhagic fever was associated with the amount of neutralising antibodies against Junin virus present in the transfused units of immune plasma. Low doses of neutralising antibodies were associated with higher mortality. A prospective study gave comparable results. A dose of no less than 3000 therapeutic units of neutralising antibodies per kg body weight is recommended. It is also suggested that the lack of effectiveness of immune… CONTINUE READING
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Monoclonal antibody therapy for Junin virus infection.

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  • Proceedings of the National Academy of Sciences of the United States of America
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