IMP3 is a novel biomarker for triple negative invasive mammary carcinoma associated with a more aggressive phenotype.

@article{Walter2009IMP3IA,
  title={IMP3 is a novel biomarker for triple negative invasive mammary carcinoma associated with a more aggressive phenotype.},
  author={Otto Walter and Manju Prasad and Shaolei Lu and Robert M Quinlan and Kathryn L Edmiston and Ashraf Khan},
  journal={Human pathology},
  year={2009},
  volume={40 11},
  pages={1528-33}
}
IMP3, an oncofetal protein, is a member of the insulin-like growth factor-II (IGF-II) mRNA-binding protein family. Its relevance as a novel biomarker in lung, pancreatic, renal, and cervical adenocarcinoma was recently revealed. However, its role in breast carcinogenesis and tumor progression is not yet established. Basal-like carcinoma was initially identified by gene expression profiling. It accounts for 15% to 30% of all breast cancers. These tumors express basal epithelial markers including… CONTINUE READING

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IMP3 expression in triple-negative breast carcinoma.

Human pathology • 2010
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