IMP2 expression distinguishes endometrioid from serous endometrial adenocarcinomas.

@article{Zhang2011IMP2ED,
  title={IMP2 expression distinguishes endometrioid from serous endometrial adenocarcinomas.},
  author={Liping Zhang and Yuxin Liu and Suyang Hao and Bruce A. Woda and Di Lu},
  journal={The American journal of surgical pathology},
  year={2011},
  volume={35 6},
  pages={868-72}
}
Among various endometrial adenocarcinomas, endometrioid carcinoma can be very difficult to separate from serous carcinomas. Various biomarkers have been studied with proven value, including p53, Ki-67, and p16. In this study, we present data on another biomarker, IMP2, which we believe is sensitive and specific. Using 320 endometrial biopsy cases, we demonstrate that IMP2 is normally expressed in all proliferative and inactive endometrial glandular cells. The pattern of such expression is… CONTINUE READING
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