IMGT/PhyloGene: an on-line tool for comparative analysis of immunoglobulin and T cell receptor genes.

@article{Elemento2003IMGTPhyloGeneAO,
  title={IMGT/PhyloGene: an on-line tool for comparative analysis of immunoglobulin and T cell receptor genes.},
  author={Olivier Elemento and Marie-Paule Lefranc},
  journal={Developmental and comparative immunology},
  year={2003},
  volume={27 9},
  pages={
          763-79
        }
}

Figures and Tables from this paper

IMGT/V-QUEST, an integrated software program for immunoglobulin and T cell receptor VJ and VDJrearrangement analysis
IMGT/V-QUEST, for 'V-QUEry and STandardization', is an integrated software program which analyses the immunoglobulin (IG) and T cell receptor (TR) rearranged nucleotide sequences. The extraordinary
IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes
IMGT/GENE-DB is the comprehensive IMGT genome database for immunoglobulin (IG) and T cell receptor (TR) genes from human and mouse, and, in development, from other vertebrates. IMGT/GENE-DB is the
IMGT(®) tools for the nucleotide analysis of immunoglobulin (IG) and T cell receptor (TR) V-(D)-J repertoires, polymorphisms, and IG mutations: IMGT/V-QUEST and IMGT/HighV-QUEST for NGS.
TLDR
IMGT/V-QUEST is the highly customized and integrated online IMGT(®) tool for the standardized analysis of the immunoglobulin (IG) or antibody and T cell receptor (TR) rearranged nucleotide sequences and the high-throughput version, IMGT/HighV- QUEST, allows the analysis of thousands of IG and TR sequences in a single run.
Using Bioinformatics Tools for the Sequence Analysis of Immunoglobulins and T Cell Receptors
  • M. Lefranc
  • Biology
    Current protocols in immunology
  • 2006
The huge potential repertoire of 1012 immunoglobulins and 1012 T cell receptors per individual results from complex mechanisms of combinatorial diversity between the variable (V), diversity (D), and
IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis
IMGT/V-QUEST is the highly customized and integrated system for the standardized analysis of the immunoglobulin (IG) and T cell receptor (TR) rearranged nucleotide sequences. IMGT/V-QUEST identifies
IMGT, the international ImMunoGeneTics information system for Immunoinformatics. Methods for querying IMGT databases, tools, and Web resources in the context of immunoinformatics.
TLDR
IMGT provides a common access to standardized data from genome, proteome, genetics, and three-dimensional (3D) structures for the IG, TR, MHC, IgSF, MhcSF, and RPI.
IMGT-ONTOLOGY, IMGT® Databases, Tools, and Web Resources for Immunoinformatics
TLDR
This work is implementing Web services for the IMGT databases and tools, the first step toward IMGTChoreography that will trigger and coordinate dynamic interactions between IMGT Web services in order to process complex significant biological and clinical requests.
IMGT ® , the international ImMunoGeneTics information system ® , the reference in immunogenetics and immunoinformatics
TLDR
IMGT®, the international ImMunoGeneTics information system® is a high quality integrated knowledge resource specialized in the immunoglobulins (IG), T cell receptors (TR), major histocompatibility complex (MHC) of human and other vertebrates, and related proteins of the immune systems (RPI).
...
...

References

SHOWING 1-10 OF 93 REFERENCES
IMGT® databases, web resources and tools for immunoglobulin and T cell receptor sequence analysis, http://imgt.cines.fr
TLDR
IMGT expertly annotated data and tools described in this paper are particularly useful for the analysis of the IG and TR rearrangements in leukemia, lymphoma and myeloma, and in translocations involving the antigen receptor loci.
IMGT, the international ImMunoGeneTics database: a high-quality information system for comparative immunogenetics and immunology.
  • M. Lefranc
  • Biology
    Developmental and comparative immunology
  • 2002
IMGT gene identification and Colliers de Perles of human immunoglobulins with known 3D structures
TLDR
The IMGT gene identification and Colliers de Perles of human immunoglobulins with known 3D structures in the Protein Data Bank are presented.
IMGT, the International ImMunoGeneTics database
TLDR
IMGT goals are to establish a common data access to all immunogenetics data, including sequences, oligonucleotide primers, gene maps and other genetic data of immunoglobulins, TcR and MHC molecules, and to provide a graphical user-friendly data access.
Nomenclature of the Human Immunoglobulin Lambda (IGL) Genes
  • M. Lefranc
  • Biology
    Experimental and Clinical Immunogenetics
  • 2001
‘Nomenclature of the Human Immunoglobulin Lambda (IGL) Genes’, the 18th report of the ‘IMGT Locus in Focus’ section, provides the first complete list of all the human IGL genes. The total number of
Human T-cell receptor variable gene segment families
TLDR
The traditional numbering of V gene segments in the order of their discovery was continued and changed when in conflict with names of other segments, and the number of more than 150 different TCRBV sequences in the database was reduced to a repertoire of only 47 functional T CRBV gene segments.
Nomenclature of the Human Immunoglobulin Heavy (IGH) Genes
  • M. Lefranc
  • Biology
    Experimental and Clinical Immunogenetics
  • 2001
‘Nomenclature of the Human Immunoglobulin Heavy (IGH) Genes’, the 16th report of the ‘IMGT Locus in Focus’ section, provides the first complete list of all the human IGH genes. The total number of
Ontology for immunogenetics: the IMGT-ONTOLOGY
TLDR
The IMGT-ONTOLOGY allows scientists and clinicians to use, for the first time, identical terms with the same meaning in immunogenetics and provides a semantic repository that will improve interoperability between specialist and generalist databases.
...
...