IMAGING HOW THE PREIMPLANTATION EMBRYO FORMS IN REAL TIME

@inproceedings{Plachta2019IMAGINGHT,
  title={IMAGING HOW THE PREIMPLANTATION EMBRYO FORMS IN REAL TIME},
  author={Nicolas Plachta},
  year={2019}
}
Preimplantation development has typically been studied using fixed specimens. To reveal the dynamics that form the embryo, we established advanced imaging technologies to visualize single-cell dynamics and molecular events in real time within the mouse embryo. With this approach, we discovered how transcription factors bind to DNA in single cells of the embryo, to regulate the first cell fate decisions during embryonic development. We also unveiled new forms of actin and microtubule… CONTINUE READING