ILAE Official Report: A practical clinical definition of epilepsy

  title={ILAE Official Report: A practical clinical definition of epilepsy},
  author={Robert S. Fisher and Carlos Acevedo and Alexis Arzimanoglou and Alicia Bogacz and Judith Helen Cross and Christian Erich Elger and Jerome Engel and Lars Forsgren and Jacqueline A. French and Mike Glynn and Dale C. Hesdorffer and B.I. Lee and Gary W Mathern and Solomon L Mosh{\'e} and Emilio Perucca and Ingrid Eileen Scheffer and Torbj{\"o}rn Tomson and Masako Watanabe and Samuel Wiebe},
Epilepsy was defined conceptually in 2005 as a disorder of the brain characterized by an enduring predisposition to generate epileptic seizures. This definition is usually practically applied as having two unprovoked seizures >24 h apart. The International League Against Epilepsy (ILAE) accepted recommendations of a task force altering the practical definition for special circumstances that do not meet the two unprovoked seizures criteria. The task force proposed that epilepsy be considered to… 

A Practical Definition of Epilepsy

Epilepsy is considered to be resolved for individuals past the applicable age of an age-dependent epilepsy syndrome or those who have remained seizure-free for the past 10 years, without seizure medicines for thepast 5 years.

Classification of Childhood Epileptic Seizures

Epilepsy is considered to be resolved for individuals who either had an age-dependent epilepsy syndrome but are now past the applicable age or who have remained seizure-free for 10 years, with no seizure medicines for the last 5 years.

Commentary: ILAE Definition of Epilepsy

In the current issue of Epilepsia, Fisher and colleagues provide a number of recommendations for practical operational definitions for epilepsy. The recommendations address three areas. 1.

Commentary: ILAE Definition of Epilepsy

  • C. Tan
  • Psychology, Medicine
  • 2014
The International League Against Epilepsy (ILAE) and the authors are to be congratulated for formulating the practical clinical definition of epilepsy, which aims to make the previous conceptual

Introduction to the Clinical Definition of Epilepsy by the ILAE President

This issue of Epilepsia contains a landmark paper addressing a topic central to the authors' discipline: “What is epilepsy?” Fisher et al. provide a consensus-driven answer by building on the 2005 conceptual definition by taking the conceptual definition into an operational dimension and provides clinical criteria that physicians can apply in everyday practice.

Commentary: ILAE Definition of Epilepsy

The point system developed from the MESS study, which can be helpful in determining if a patient should be treated immediately or can if treatment can be deferred until the occurrence of a second unprovoked seizure, is presented.

The Revised Definition and Classification of Epilepsy for Neurodiagnostic Technologists

The classical definition of epilepsy as a person having two or more unprovoked seizures more than 24 hours apart has been expanded also to include those with one seizure and a high likelihood of having another.

Surgical Management of Drug Resistant Epilepsy

This work aims to review surgical outcome for drug resistant epilepsy of different causes to identify which patient would get the most benefit to determine whether or not epilepsy surgery can be done and to define its chances of risk and benefit.

Diagnosis of epilepsy after first seizure. Introducing the SWISS FIRST study

This Switzerland-wide observational study aims to recruit patients that were admitted to the emergency department with the referral diagnosis of a first and unprovoked seizure, and makes use of optimized MRI protocols to identify potential structural epileptogenic lesions, introduces new imaging-based markers of epileptogenecity, and uses most recent postprocessing methods as automatic morphometry, spike map analysis, and functional connectivity.



Epidemiology of the epilepsies.

It is likely that field studies miss patients unless sensitive screening techniques for all epileptic phenomena are included in the case ascertainment and it is important to reach a balance between sensitivity and specificity, which has not yet been satisfactorily achieved.

Unprovoked Status Epilepticus: The Prognosis for Otherwise Normal Children With Focal Epilepsy

SE often recurs but apparently has little influence on long-term intellectual and seizure outcome in normally intelligent children with focal epilepsy.

Epileptic Seizures and Epilepsy: Definitions Proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)

Summary:  The International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE) have come to consensus definitions for the terms epileptic seizure and epilepsy. An

The first unprovoked, untreated seizure in childhood: a hospital based study of the accuracy of the diagnosis, rate of recurrence, and long term outcome after recurrence. Dutch study of epilepsy in childhood

The overall prognosis for a child presenting with a single seizure is excellent, even if treatment with antiepileptic drugs is not immediately instituted, as well as the recurrence rate within two years, the risk factors for recurrence, and the long term outcome two years after recurrence.

Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005–2009

The International League Against Epilepsy (ILAE) Commission on Classification and Terminology has revised concepts, terminology, and approaches for classifying seizures and forms of epilepsy.

Prevalence of Epilepsy in Rochester, Minnesota: 1940–1980

The prevalence of epilepsy in Rochester, Minnesota has been determined for a specific date in each of 5 decennial census years since 1940, and was highest in the oldest age groups after 1950.

The risk of seizure recurrence following a first unprovoked seizure

There is considerable agreement among studies concerning the recurrence risk following a first seizure, and much of the discrepancies among studies can be explained by differences in study methods and distributions of important prognostic factors.

Evaluation of first nonfebrile seizures.

Treatment with an antiepileptic drug after a first seizure does not prevent epilepsy in the long term, but it decreases the short-term likelihood of a second seizure, so patients with persistent decreased mental status or a new focal neurologic abnormality should be treated.