IL4 gene polymorphism and previous malaria experiences manipulate anti-Plasmodium falciparum antibody isotype profiles in complicated and uncomplicated malaria

@inproceedings{Tangteerawatana2009IL4GP,
  title={IL4 gene polymorphism and previous malaria experiences manipulate anti-Plasmodium falciparum antibody isotype profiles in complicated and uncomplicated malaria},
  author={Piyatida Tangteerawatana and Hedvig Perlmann and Masashi Hayano and Thareerat Kalambaheti and Marita Troye-Blomberg and Srisin Khusmith},
  booktitle={Malaria Journal},
  year={2009}
}
The IL4-590 gene polymorphism has been shown to be associated with elevated levels of anti-Plasmodium falciparum IgG antibodies and parasite intensity in the malaria protected Fulani of West Africa. This study aimed to investigate the possible impact of IL4-590C/T polymorphism on anti-P. falciparum IgG subclasses and IgE antibodies levels and the alteration of malaria severity in complicated and uncomplicated malaria patients with or without previous malaria experiences. Anti-P.falciparum IgG… CONTINUE READING

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