IL28B polymorphisms predict the virological response to standard therapy in patients with chronic hepatitis C virus genotype 4 infection

@inproceedings{Abdo2013IL28BPP,
  title={IL28B polymorphisms predict the virological response to standard therapy in patients with chronic hepatitis C virus genotype 4 infection},
  author={Ayman Assad Abdo and Mohammed Noreen Al-Ahdal and Saira Sarfraz Khalid and Ahmad Salem Helmy and Faisal M Sanai and Khalid A Alswat and Waleed K Al-Hamoudi and Safiyya Mohamed Ali and Hamad Ibrahim Al-Ashgar and Abdallah Al-Mdani and Ali Albenmousa and Faleh Zaid Al Faleh and Mashael R. Al-Anazi and Nisreen Z. Khalaf and Ahmed A Al-Qahtani},
  booktitle={Hepatology international},
  year={2013}
}
BACKGROUND Genome-wide association studies have recently revealed that several single-nucleotide polymorphisms (SNPs) in the interleukin (IL) 28B genes can predict the sustained virological response (SVR) to pegylated interferon-α2a/b plus ribavirin in hepatitis C virus (HCV)-genotype 1 patients. However, data for patients infected with HCV genotype 4 (HCV-G4) are limited. AIM We analyzed the association of IL28B SNPs (hematological, biochemical, virological, and pathological factors) with… CONTINUE READING

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