IL13 promoter polymorphism 1112C/T modulates the adverse effect of tobacco smoking on lung function.

@article{Sadeghnejad2007IL13PP,
  title={IL13 promoter polymorphism 1112C/T modulates the adverse effect of tobacco smoking on lung function.},
  author={Alireza Sadeghnejad and Deborah A. Meyers and Matteo Bottai and David A Sterling and Eugene Bleecker and Jill A. Ohar},
  journal={American journal of respiratory and critical care medicine},
  year={2007},
  volume={176 8},
  pages={748-52}
}
RATIONALE Although the duration and amount of cigarette smoking correlate with reduction in pulmonary function, there is still variation among individual responses. IL-13 is involved in pulmonary inflammation, remodeling, and susceptibility to chronic obstructive pulmonary disease (COPD). OBJECTIVES We investigated whether the relationships between smoking and the lung function measures FEV(1) and FEV(1)/FVC ratio are modulated by IL13 polymorphisms. METHODS Smokers (>or=20 pack-years… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

Biomarkers in chronic obstructive pulmonary disease: confusing or useful?

International journal of chronic obstructive pulmonary disease • 2014
View 1 Excerpt

Similar Papers

Loading similar papers…