IL-8 degradation by Porphyromonas gingivalis proteases.

@article{Zhang1999IL8DB,
  title={IL-8 degradation by Porphyromonas gingivalis proteases.},
  author={J. Zhang and H. Dong and Shelby Kashket and Margaret J. Duncan},
  journal={Microbial pathogenesis},
  year={1999},
  volume={26 5},
  pages={
          275-80
        }
}
Gingival epithelial cells are the primary barrier to infection by periodontal pathogens. The production of chemotactic cytokines, including interleukin-8 (IL-8), is one mechanism the host uses in response to infection. In this study it was found that both gingival and oral epithelial cells produced IL-8, but after infection with the periodontal pathogen Porphyromonas gingivalis, accumulation of the cytokine could not be detected. Northern analysis established that infected epithelial cells… 
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