IL-6 promoter polymorphism in patients with rheumatoid arthritis.

@article{Pawlik2005IL6PP,
  title={IL-6 promoter polymorphism in patients with rheumatoid arthritis.},
  author={Andrzej Pawlik and Joanna Wrześniewska and Marcin Florczak and Barbara Gawrońska-Szklarz and Magdalena Herczyńska},
  journal={Scandinavian journal of rheumatology},
  year={2005},
  volume={34 2},
  pages={109-13}
}
OBJECTIVE Rheumatoid arthritis (RA) is a chronic inflammatory disease in which cytokines play an important role. The aim of the present study was to examine the interleukin-6 (IL-6) -174 promoter polymorphism in patients with RA and its association with disease susceptibility and activity. METHODS The study included 98 patients with RA diagnosed according to the criteria of the American College of Rheumatology. Polymerase chain reaction (PCR) amplification was used for analysis of the… CONTINUE READING
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