IL-6-like cytokines and cancer cachexia

@article{Barton2001IL6likeCA,
  title={IL-6-like cytokines and cancer cachexia},
  author={Beverly E. Barton},
  journal={Immunologic Research},
  year={2001},
  volume={23},
  pages={41-58}
}
An estimated 30% of cancer deaths are attributed to cachexia and its consequences. Cachexia (wasting syndrome) is the hypercatabolism of the body's carbon sources, proteins and lipids, for conversion into energy. It is induced by a variety of pathological conditions, including cancer. Among the inflammatory responses to cancer is the synthesis of cytokines, including IL-6 and related cytokines. These cytokines have been found to induce cach exia by altering metabolism of lipids and proteins. IL… CONTINUE READING
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  • 2014
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