IL-6 is required for airway mucus production induced by inhaled fungal allergens.

@article{Neveu2009IL6IR,
  title={IL-6 is required for airway mucus production induced by inhaled fungal allergens.},
  author={Wendy A. Neveu and J. Belaish Allard and Oliver Dienz and Matthew J Wargo and Gennaro Ciliberto and Laurie A. Whittaker and Mercedes del Rinc{\'o}n},
  journal={Journal of immunology},
  year={2009},
  volume={183 3},
  pages={
          1732-8
        }
}
Allergic asthma is caused by inhaled allergens and is characterized by airway eosinophilia, as well as mucus hypersecretion, which can lead to airflow obstruction. Despite the association of increased IL-6 levels with human atopic asthma, the contribution of IL-6 to the development of allergic airway inflammation triggered by inhaled allergens remains unclear. In this study, we examined the role of IL-6 in a mouse model of allergic airway inflammation induced by direct airway exposure to… CONTINUE READING
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