IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation

@inproceedings{Wei2011IL6II,
  title={IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation},
  author={Hongen Wei and Hua Zou and Ashfaq M. Sheikh and Mazhar N. Malik and Carl Dobkin and William Ted Brown and Xiaohong Li},
  booktitle={Journal of Neuroinflammation},
  year={2011}
}
Although the cellular mechanisms responsible for the pathogenesis of autism are not understood, a growing number of studies have suggested that localized inflammation of the central nervous system (CNS) may contribute to the development of autism. Recent evidence shows that IL-6 has a crucial role in the development and plasticity of CNS. Immunohistochemistry studies were employed to detect the IL-6 expression in the cerebellum of study subjects. In vitro adenoviral gene delivery approach was… CONTINUE READING
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