IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses.

Abstract

IL-6 is induced often together with the proinflammatory cytokines TNFalpha and IL-1 in many alarm conditions, and circulating IL-6 plays an important role in the induction of acute phase reactions. However, whether this endogenous IL-6 plays any additional pro- or antiinflammatory roles in local or systemic responses remains unclear. In this study, the role… (More)

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@article{Xing1998IL6IA, title={IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses.}, author={Zhen Xing and Jack Gauldie and Gerard Cox and Heinz Baumann and Manel Jordana and Xiao Feng Lei and M K Achong}, journal={The Journal of clinical investigation}, year={1998}, volume={101 2}, pages={311-20} }