IL-6 cytokine family and signal transduction: a model of the cytokine system

@article{Hibi1996IL6CF,
  title={IL-6 cytokine family and signal transduction: a model of the cytokine system},
  author={Masahiko Hibi and Koichi Nakajima and Toshio Hirano},
  journal={Journal of Molecular Medicine},
  year={1996},
  volume={74},
  pages={1-12}
}
The interleukin 6 (IL-6) cytokine family, which includes IL-6, leukemia inhibitory factor (LIF), oncostatin M (OSM), ciliary neurotrophic factor (CNTF), IL-11 and cardiotrophin-1 (CT-1), exhibits pleiotropy and redundancy in biological activities. The IL-6 family cytokines exhibit a helical structure. Their receptors belong to the type 1 cytokine receptor family. The receptors of the IL-6 family cytokines share a receptor subunit, which explains one of the mechanisms of functional redundancy… CONTINUE READING
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Characterization of interleukin - 11 receptor and protein tyrosine phosphorylation induced by interleukin - ll in mouse 3 T 3L 1 cells

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