IL-4 gene polymorphisms and their association with atopic asthma and allergic rhinitis in Pakistani patients.

@article{Micheal2013IL4GP,
  title={IL-4 gene polymorphisms and their association with atopic asthma and allergic rhinitis in Pakistani patients.},
  author={Shazia Micheal and Khalid Minhas and Muhammad Kashif Ishaque and Farid Uddin Ahmed and Asifa Ahmed},
  journal={Journal of investigational allergology & clinical immunology},
  year={2013},
  volume={23 2},
  pages={107-11}
}
BACKGROUND AND OBJECTIVE Interleukin (IL) 4 is a cytokine that mediates allergic responses. Different single nucleotide polymorphisms (SNPs) can influence the immune response mediated by cytokines. The aim of the present study was to investigate the possible association between IL-4 polymorphisms and allergic rhinitis and atopic asthma. METHODS A total of 214 atopic patients (108 with asthma and 106 with allergic rhinitis) and 120 healthy controls from Pakistan were genotyped for IL-4 SNPs C… CONTINUE READING
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The -590C/T IL4 single-nucleotide polymorphism as a genetic factor of atopic allergy

  • RM deGuia, JD Ramos
  • Int J Mol Epidemiol Genet
  • 2010
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