IL-37 and leprosy: A novel cytokine involved in the host response to Mycobacterium leprae infection.

@article{Sousa2018IL37AL,
  title={IL-37 and leprosy: A novel cytokine involved in the host response to Mycobacterium leprae infection.},
  author={Jorge Rodrigues de Sousa and Renata Lima Prudente and Leonidas Braga Dias Junior and Francisca Regina Oliveira Carneiro and M{\'i}rian Nacagami Sotto and Juarez Ant{\^o}nio Sim{\~o}es Quaresma},
  journal={Cytokine},
  year={2018},
  volume={106},
  pages={89-94}
}
Leprosy is a chronic infectious granulomatous disease caused by Mycobacterium leprae, in which the clinical outcome depends on the pattern of the host immune response. Because it is a spectral disease, leprosy is a good model for studying the immunology of the pathogen-host relationship. Although previous studies have characterized the participation of cytokine profiles such as Th1, Th2, Th7, Treg, Th9, and Th22 responses in leprosy, the role of new cytokines such as IL-37 have not yet been… CONTINUE READING