IL-33 promotes Staphylococcus aureus-infected wound healing in mice.

  title={IL-33 promotes Staphylococcus aureus-infected wound healing in mice.},
  author={Hui Qiu Yin and Xiangyong Li and Shilian Hu and Tao Liu and Baohong Yuan and Qian Ni and Fang Lan and Xiaochun Luo and Hongbiao Gu and Fang Zheng},
  journal={International immunopharmacology},
  volume={17 2},
Interleukin (IL)-33, a newly identified member of IL-1 family of cytokines, plays a crucial role in polarizing Th2-associated immune responses. Recently growing evidence indicates that IL-33 also represents an important mediator of mucosal healing and epithelial restoration. In this study, we investigated the effect of IL-33 on antimicrobial infection and wound healing using a Staphylococcus aureus-infected incision model in mice. Our findings showed that the expression of IL-33 mRNA and… CONTINUE READING