IL-33 induces skin inflammation with mast cell and neutrophil activation.

@article{Hueber2011IL33IS,
  title={IL-33 induces skin inflammation with mast cell and neutrophil activation.},
  author={Axel J Hueber and Jos{\'e} Carlos F Alves-Filho and Darren Lee Asquith and Chesney Michels and Neal L Millar and James H. Reilly and Gerard J Graham and Foo Yew Eddy Liew and Ashley M. Miller and Iain B. Mcinnes},
  journal={European journal of immunology},
  year={2011},
  volume={41 8},
  pages={2229-37}
}
Psoriasis is a common chronic autoimmune condition of the skin characterized by hyperplasia of epidermal keratinocytes associated with pro-inflammatory cytokines. IL-33 is a new member of the IL-1 superfamily that signals through the ST2 receptor and was originally defined as an inducer of T helper 2 (Th2) cytokines. Recently, broader immune activatory… CONTINUE READING